Epigenetic marker (LINE-1 promoter) methylation level was associated with occupational lead exposure.

@article{Li2013EpigeneticM,
  title={Epigenetic marker (LINE-1 promoter) methylation level was associated with occupational lead exposure.},
  author={Chunping Li and Xiaolin Yang and Ming Xu and Jinlong Zhang and Nan Sun},
  journal={Clinical toxicology},
  year={2013},
  volume={51 4},
  pages={225-9}
}
CONTEXT Occupational and environmental exposures to lead (Pb) are a worldwide concern. DNA methylation plays an important role in the development of Pb toxicity. Here, we try to find out the evidence to prove that the methylation of the LINE-1 promoter may be involved in Pb toxicity. METHODS To determine whether the methylation level of the LINE-1 is associated with the risk of Pb poisoning, we first constructed a Pb acetate-treated cell model to detect the association between LINE-1… CONTINUE READING