Epigenetic inheritance through the female germ-line: The known, the unknown, and the possible.

@article{Clarke2015EpigeneticIT,
  title={Epigenetic inheritance through the female germ-line: The known, the unknown, and the possible.},
  author={Hugh J Clarke and Karl-Fr{\'e}d{\'e}ric Vieux},
  journal={Seminars in cell & developmental biology},
  year={2015},
  volume={43},
  pages={106-116}
}
Although genetic mutations have long been known to influence gene expression and individual phenotype, studies emerging over the past decade indicate that such changes can also be induced in the absence of alterations in base-sequence. Epigenetically driven changes in gene expression or phenotype, when they are transmitted to succeeding generations, represent an entirely new mechanism that could generate heritable variation in a population. To understand the mechanistic basis of epigenetic… CONTINUE READING