Epigenetic inheritance of metabolic state.

  title={Epigenetic inheritance of metabolic state.},
  author={Rebecca A Somer and Carl S Thummel},
  journal={Current opinion in genetics & development},
As the incidence of complex metabolic disease increases in developed countries, so too does the need to understand the causes and risk factors for these disorders. In addition to the well-known contribution of genetics and environment to metabolic dysfunction, many studies have demonstrated that a significant degree of non-genetic heritable risk can be transmitted from parents to offspring over multiple generations. Understanding the mechanisms by which this occurs could change how we study and… CONTINUE READING
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Bagijn MP et al.: piRNAs can trigger a multigenerational epigenetic memory in the germline of C

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