Epigenetic information in chromatin and cancer.

Abstract

It is now widely recognised that epigenetic changes are implicated in human cancer. Epigenetic information in chromatin (known as the 'histone code') has been proposed to extend and modulate the genetic (DNA) code in the regulation of key cellular processes. Histone modifications and histone modifying complexes have been traditionally associated with… (More)
DOI: 10.1016/S0959-8049(09)70082-6

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