Epigenetic control of RNA polymerase I transcription in mammalian cells.

@article{Grummt2013EpigeneticCO,
  title={Epigenetic control of RNA polymerase I transcription in mammalian cells.},
  author={Ingrid Grummt and Gernot L{\"a}ngst},
  journal={Biochimica et biophysica acta},
  year={2013},
  volume={1829 3-4},
  pages={393-404}
}
rRNA synthesis is regulated by genetic and epigenetic mechanisms. Epigenetic states are metastable, changing in response to appropriate signals, thereby modulating transcription in vivo. The establishment, maintenance and reversal of epigenetic features are fundamental for the cell's ability to 'remember' past events, to adapt to environmental changes or developmental cues and to propagate this information to the progeny. As packaging into chromatin is critical for the stability and integrity… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 39 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 114 references

Similar Papers

Loading similar papers…