Epigenetic changes in tumor microenvironment.

@article{Dey2011EpigeneticCI,
  title={Epigenetic changes in tumor microenvironment.},
  author={Pranab Dey},
  journal={Indian journal of cancer},
  year={2011},
  volume={48 4},
  pages={507-12}
}
The drama of cancer is not the solo performance of the malignant cells. Microenvironment of the tumor has significant contribution in carcinogenesis. Recent evidences show distinct gene promoter methylation in stromal cells of various malignant and pre-malignant tumors. These changes probably create unique tumor microenvironment, which is responsible for initiation, proliferation, invasion, and metastasis of tumor cells. In this mini review the role of epigenetic changes of tumor… CONTINUE READING

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