Epigenetic changes and nontargeted radiation effects—Is there a link?

@article{Kovalchuk2008EpigeneticCA,
  title={Epigenetic changes and nontargeted radiation effects—Is there a link?},
  author={O. V. Kovalchuk and Janet E. Baulch},
  journal={Environmental and Molecular Mutagenesis},
  year={2008},
  volume={49}
}
It is now well accepted that the effects of ionizing radiation (IR) exposure can be noticed far beyond the borders of the directly irradiated tissue. IR can affect neighboring cells in the proximity, giving rise to a bystander effect. IR effects can also span several generations and influence the progeny of exposed parents, leading to transgeneration effects. Bystander and transgeneration IR effects are linked to the phenomenon of the IR‐induced genome instability that manifests itself as… 
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