Epigenetic alterations in hippocampus of SAMP8 senescent mice and modulation by voluntary physical exercise

Abstract

The senescence-accelerated SAMP8 mouse model displays features of cognitive decline and Alzheimer's disease. With the purpose of identifying potential epigenetic markers involved in aging and neurodegeneration, here we analyzed the expression of 84 mature miRNAs, the expression of histone-acetylation regulatory genes and the global histone acetylation in… (More)
DOI: 10.3389/fnagi.2014.00051

Topics

6 Figures and Tables

Statistics

010020020142015201620172018
Citations per Year

270 Citations

Semantic Scholar estimates that this publication has 270 citations based on the available data.

See our FAQ for additional information.

Cite this paper

@inproceedings{CosnToms2014EpigeneticAI, title={Epigenetic alterations in hippocampus of SAMP8 senescent mice and modulation by voluntary physical exercise}, author={Marta Cos{\'i}n-Tom{\'a}s and Mar{\'i}a Jes{\'u}s {\'A}lvarez-L{\'o}pez and Sandra Sanchez-Roige and Jaume F. Lalanza and Sergi Bayod and C. Bartual Sanfeliu and M Pall{\`a}s and Rosa Mar{\'i}a Escorihuela and Perla Kaliman}, booktitle={Front. Aging Neurosci.}, year={2014} }