Epigenetic Regulation of Werner Syndrome Gene in Age-Related Cataract

@inproceedings{Zhu2015EpigeneticRO,
  title={Epigenetic Regulation of Werner Syndrome Gene in Age-Related Cataract},
  author={Xi Zhu and Guowei Zhang and Lihua Kang and Huaijin Guan},
  booktitle={Journal of ophthalmology},
  year={2015}
}
Purpose. To examine the promoter methylation and histone modification of WRN (Werner syndrome gene), a DNA repair gene, and their relationship with the gene expression in age-related cataract (ARC) lens. Methods. We collected the lenses after cataract surgery from 117ARC patients and 39 age-matched non-ARC. WRN expression, DNA methylation and histone modification around the CpG island were assessed. The methylation status of Human-lens-epithelium cell (HLEB-3) was chemically altered to observe… CONTINUE READING
Tweets
This paper has been referenced on Twitter 2 times. VIEW TWEETS

From This Paper

Figures, tables, and topics from this paper.

References

Publications referenced by this paper.
SHOWING 1-10 OF 39 REFERENCES

Similar Papers

Loading similar papers…