Epigenetic Modifications Unlock the Milk Protein Gene Loci during Mouse Mammary Gland Development and Differentiation

@inproceedings{Rijnkels2013EpigeneticMU,
  title={Epigenetic Modifications Unlock the Milk Protein Gene Loci during Mouse Mammary Gland Development and Differentiation},
  author={Monique Rijnkels and Courtneay Freeman-Zadrowski and Jaime Agust{\'i}n S{\'a}nchez Hern{\'a}ndez and Vani Potluri and Liguo Wang and Wei Li and Danielle G. Lemay},
  booktitle={PloS one},
  year={2013}
}
BACKGROUND Unlike other tissues, development and differentiation of the mammary gland occur mostly after birth. The roles of systemic hormones and local growth factors important for this development and functional differentiation are well-studied. In other tissues, it has been shown that chromatin organization plays a key role in transcriptional regulation and underlies epigenetic regulation during development and differentiation. However, the role of chromatin organization in mammary gland… CONTINUE READING

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