Epigenetic Markers for Molecular Detection of Prostate Cancer

  title={Epigenetic Markers for Molecular Detection of Prostate Cancer},
  author={Vera L{\'u}cia Costa and Rui Henrique and Carmen Jer{\'o}nimo},
  booktitle={Disease markers},
Prostate cancer is a highly prevalent malignancy, which is clinically silent but curable while organ-confined. Because available screening methods show poor sensitivity and specificity, the development of new molecular markers is warranted. Epigenetic alterations, mainly promoter hypermethylation of cancer-related genes, are common events in prostate cancer and might be used as cancer biomarkers. Moreover, the development of quantitative, high-throughput techniques to assess promoter… CONTINUE READING


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