Epigenetic Inactivation of the SFRP1 Gene in Esophageal Squamous Cell Carcinoma


The secreted frizzled-related protein 1 (SFRP1) gene, as a Wnt signaling modulator, is frequently inactivated by promoter methylation in many tumors including gastric cancer, breast cancer, oral squamous cell carcinoma, and esophageal adenocarcinoma. However, the role of SFRP1 in esophageal squamous cell carcinoma (ESCC) is not clear. In this study, we… (More)
DOI: 10.1007/s10620-011-1734-7


8 Figures and Tables