Epigenetic Control of MicroRNA Expression and Aging

  title={Epigenetic Control of MicroRNA Expression and Aging},
  author={Ruqiang Liang and David J. Bates and Eugenia Wang},
  booktitle={Current genomics},
MicroRNAs are a major category among the noncoding RNA fraction that negatively regulate gene expression at the post-transcriptional level, by either degrading the target messages or inhibiting their translation. MicroRNAs may be referred to as 'dimmer switches' of gene expression, because of their ability to repress gene expression without completely silencing it. Whether through up-regulating specific groups of microRNAs to suppress unwanted gene expressions, or by down-regulating other… CONTINUE READING


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