Epigenetic Activation and Silencing of the Gene that Encodes IFN-γ

@inproceedings{Aune2013EpigeneticAA,
  title={Epigenetic Activation and Silencing of the Gene that Encodes IFN-γ},
  author={Thomas M. Aune and Patrick L. Collins and Sarah P. Collier and Melodie A. Henderson and Shaojing Chang},
  booktitle={Front. Immunol.},
  year={2013}
}
Transcriptional activation and repression of genes that are developmentally regulated or exhibit cell-type specific expression patterns is largely achieved by modifying the chromatin template at a gene locus. Complex formation of stable epigenetic histone marks, loss or gain of DNA methylation, alterations in chromosome conformation, and specific… CONTINUE READING