Epigallocatechin gallate preserves endothelial function by reducing the endogenous nitric oxide synthase inhibitor level.

@article{Tang2006EpigallocatechinGP,
  title={Epigallocatechin gallate preserves endothelial function by reducing the endogenous nitric oxide synthase inhibitor level.},
  author={Wei-Jun Tang and Chang-ping Hu and M Chen and Pan-yue Deng and Yuanjian Li},
  journal={Canadian journal of physiology and pharmacology},
  year={2006},
  volume={84 2},
  pages={163-71}
}
Asymmetric dimethylarginine (ADMA), the endogenous nitric oxide synthase inhibitor, is thought to be a key factor contributing to endothelial dysfunction. Tea catechins can cause an endothelium-dependent vasorelaxation. The present study examined the effect of epigallocatechin gallate (EGCG), the major component of tea catechins, on endothelial dysfunction induced by native low density lipoprotein (LDL) in rats and oxidized LDL (ox-LDL) in cultured endothelial cells, and whether the protective… CONTINUE READING

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