Epigallocatechin gallate inhibits hepatitis B virus via farnesoid X receptor alpha

@article{Xu2016EpigallocatechinGI,
  title={Epigallocatechin gallate inhibits hepatitis B virus via farnesoid X receptor alpha},
  author={Jun Xu and Weizhen Gu and Chaoyan Li and Xiao Li and Guozhen Xing and Yan Li and Yanhui Song and Wenming Zheng},
  journal={Journal of Natural Medicines},
  year={2016},
  volume={70},
  pages={584-591}
}
Plants possess various natural antiviral properties. Epigallocatechin-3-gallate (EGCG), a major component of green tea, inhibits a variety of viruses. However, the clinical application of EGCG is currently hindered by a scarcity of information on its molecular mechanism of action. In the present study, we examined the anti-HBV (hepatitis B virus) effects of catechins from green tea at the transcriptional and antigen-expression levels, as well as the associated molecular mechanisms, because HBV… CONTINUE READING
BETA

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