Epigallocatechin-3-gallate protects against cisplatin-induced nephrotoxicity by inhibiting endoplasmic reticulum stress-induced apoptosis.

Abstract

Cisplatin (CP)-induced nephrotoxicity hampers its application in clinic. Green tea, particularly its predominant polyphenolic constituent epigallocatechin-3-gallate (EGCG), possesses anti-inflammatory, antioxidant, and anti-apoptotic properties. The present study was designed to investigate the protective effects of EGCG against CP-induced nephrotoxicity in… (More)
DOI: 10.1177/1535370215573394

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@article{Chen2015Epigallocatechin3gallatePA, title={Epigallocatechin-3-gallate protects against cisplatin-induced nephrotoxicity by inhibiting endoplasmic reticulum stress-induced apoptosis.}, author={Binbin Chen and Guangyi Liu and Peimei Zou and Xing Li and Qiufa Hao and Bei Jiang and Xiangdong Yang and Zhao Hu}, journal={Experimental biology and medicine}, year={2015}, volume={240 11}, pages={1513-9} }