Epigallocatechin-3-gallate-induced stress signals in HT-29 human colon adenocarcinoma cells.

@article{Chen2003Epigallocatechin3gallateinducedSS,
  title={Epigallocatechin-3-gallate-induced stress signals in HT-29 human colon adenocarcinoma cells.},
  author={Chi Lan Chen and Guoxiang Shen and Vidya Hebbar and Rong Hu and Edward D. Owuor and A-N Tony Kong},
  journal={Carcinogenesis},
  year={2003},
  volume={24 8},
  pages={1369-78}
}
Epigallocatechin-3-gallate (EGCG), a major component in green tea polyphenols, has been proven to suppress colonic tumorigenesis in animal models and epidemiological studies. As EGCG is retained in the gastrointestinal tract after oral administration, this pharmacokinetics property gives it the potential to function as a chemopreventive agent against colon cancer. In this study, human colorectal carcinoma HT-29 cells were treated with EGCG to examine the anti-proliferative and pro-apoptotic… CONTINUE READING