Epigallocatechin-3-gallate impairs chemokine production in human colon epithelial cell lines.

  title={Epigallocatechin-3-gallate impairs chemokine production in human colon epithelial cell lines.},
  author={D{\'e}bora Porath and Christoph Riegger and Juergen Drewe and Joseph Schwager},
  journal={The Journal of pharmacology and experimental therapeutics},
  volume={315 3},
A major component in green tea, epigallocatechin-3-gallate (EGCG), is reported to interfere with different steps of a number of inflammatory pathways. After oral administration, EGCG is retained in the gastrointestinal tract, where it is thought to exert preventive functions against inflammatory bowel disease and colon cancer. In this study, the human colon adenocarcinoma cell lines HT29 and T84 were used to investigate the effect of EGCG on intestinal inflammation. HT29 and T84 cells were… CONTINUE READING


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EGCG ( TeavigoTM ) modulates mediators involved in gastro - intestinal inflammation

  • D Porath, C Riegger, J Schwager
  • Clin Investig Med
  • 2004
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