Epifriedelanol from the root bark of Ulmus davidiana inhibits cellular senescence in human primary cells.

@article{Yang2011EpifriedelanolFT,
  title={Epifriedelanol from the root bark of Ulmus davidiana inhibits cellular senescence in human primary cells.},
  author={Hyo Hyun Yang and Jong Keun Son and Bo Chan Jung and Ming Shan Zheng and Jae-Ryong Kim},
  journal={Planta medica},
  year={2011},
  volume={77 5},
  pages={
          441-9
        }
}
Since cellular senescence involves organismal aging as well as diverse diseases, aging intervention might contribute to inhibit the aging process as well as aging-associated diseases. We tried to search for effective compounds from the root bark of ULMUS DAVIDIANA that are able to inhibit cellular senescence in human fibroblasts (HDFs) and human umbilical vein endothelial cells (HUVECs). Twenty-two compounds from the root bark of U. DAVIDIANA were isolated and screened for their inhibitory… 

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