Epifriedelanol from the root bark of Ulmus davidiana inhibits cellular senescence in human primary cells.

@article{Yang2011EpifriedelanolFT,
  title={Epifriedelanol from the root bark of Ulmus davidiana inhibits cellular senescence in human primary cells.},
  author={Hyo Hyun Yang and Jong Keun Son and Bo Chan Jung and Ming Shan Zheng and Jae-Ryong Kim},
  journal={Planta medica},
  year={2011},
  volume={77 5},
  pages={
          441-9
        }
}
Since cellular senescence involves organismal aging as well as diverse diseases, aging intervention might contribute to inhibit the aging process as well as aging-associated diseases. We tried to search for effective compounds from the root bark of ULMUS DAVIDIANA that are able to inhibit cellular senescence in human fibroblasts (HDFs) and human umbilical vein endothelial cells (HUVECs). Twenty-two compounds from the root bark of U. DAVIDIANA were isolated and screened for their inhibitory… 
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Quercetin-3-O-β-d-glucuronide isolated from Polygonum aviculare inhibits cellular senescence in human primary cells

Data imply that compound 9 represses cellular senescence in human primary cells and might be useful for the development of dietary supplements or cosmetics that ameliorate tissue aging or aging-associated diseases.

Quercetin-3-O-β-d-glucuronide isolated from Polygonum aviculare inhibits cellular senescence in human primary cells

Data imply that compound 9 represses cellular senescence in human primary cells and might be useful for the development of dietary supplements or cosmetics that ameliorate tissue aging or aging-associated diseases.

Inhibitory effects of quercetagetin 3,4′-dimethyl ether purified from Inula japonica on cellular senescence in human umbilical vein endothelial cells

It is suggested that compound 4 represses cellular senescence in HUVECs and might be useful for the development of dietary supplements or cosmetics that alleviate tissue aging or age-related diseases.

Inhibitory effects of quercetagetin 3,4′-dimethyl ether purified from Inula japonica on cellular senescence in human umbilical vein endothelial cells

It is suggested that compound 4 represses cellular senescence in HUVECs and might be useful for the development of dietary supplements or cosmetics that alleviate tissue aging or age-related diseases.

Inhibitory effects of (−)-loliolide on cellular senescence in human dermal fibroblasts

It is implied that (−)-loliolide rescues cellular senescence in HDFs and might be useful for the development of dietary supplements or cosmetics that ameliorate tissue aging or age-associated diseases.

Inhibitory effects of (−)-loliolide on cellular senescence in human dermal fibroblasts

It is implied that (−)-loliolide rescues cellular senescence in HDFs and might be useful for the development of dietary supplements or cosmetics that ameliorate tissue aging or age-associated diseases.

Chemical constituents of Hericium erinaceum associated with the inhibitory activity against cellular senescence in human umbilical vascular endothelial cells

The active compound of Hericium erinaceum may inspire the development of a new pharmacologically useful substance to be used in the treatment and prevention of age-related diseases.

Effects of bioactive compounds on senescence and components of senescence associated secretory phenotypes in vitro.

This review summarizes how the biological compounds listed above affect cell morphology, cell proliferation, specific cell functions, the activity of senescence-associated β-galactosidase (SA-β-gal), the shortening of telomeres and reduction of telomerase activity, production of intracellular reactive oxygen species (ROS) and lipid peroxidation products, expression of antioxidant enzymes and expression of p53 and p21 are summarized.

Chemical Constituents of Ulmus minor subsp. minor Fruits Used in the Italian Phytoalimurgic Tradition and Their Anti-inflammatory Activity Evaluation

Several isolated compounds from U. minor samaras supporting their possible alimentary use are highlighted, including one new flavan-3-ol, one new trihydroxy fatty acid, and two glycosylated flavonoids whose NMR data are not available in the literature.

Inhibitory Effects of AF-343, a Mixture of Cassia tora L., Ulmus pumila L., and Taraxacum officinale, on Compound 48/80-Mediated Allergic Responses in RBL-2H3 Cells

AF-343 attenuates allergic responses via suppression of β-hexosaminidase release, IL-4 and TNF-α secretion, and ROS generation, perhaps through mechanisms related to catechin, aurantio-obtusin, and chicoric acid.

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