Epidural pain relief in labour: potencies of levobupivacaine and racemic bupivacaine.

  title={Epidural pain relief in labour: potencies of levobupivacaine and racemic bupivacaine.},
  author={Gordon R Lyons and Malachy Columb and Rowan C. Wilson and Robert V Johnson},
  journal={British journal of anaesthesia},
  volume={81 6},
We have compared the minimum local analgesic concentrations (MLAC) of levobupivacaine relative to racemic bupivacaine in a prospective, randomized, double-blind, sequential allocation study. Women in labour were given a 20-ml bolus of epidural levobupivacaine or bupivacaine diluted to a concentration determined by up-down sequential allocation. The initial concentration was 0.07% w/v for both drugs. Efficacy was defined using a visual analogue pain score (VAPS) at 10 mm or less within 30 min… CONTINUE READING
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