Epidermodysplasia verruciformis and human papilloma virus

@article{Gewirtzman2008EpidermodysplasiaVA,
  title={Epidermodysplasia verruciformis and human papilloma virus},
  author={Aron J Gewirtzman and Brenda L. Bartlett and Stephen K. Tyring},
  journal={Current Opinion in Infectious Diseases},
  year={2008},
  volume={21},
  pages={141–146}
}
Purpose of reviewDespite its rarity, epidermodysplasia verruciformis was addressed in depth in recent literature. Patients are afflicted by persistent human papillomavirus infections and develop cutaneous malignancies more frequently and younger than in the general population. The disease is therefore considered a model for a viral role in cutaneous oncogenesis, although implication is controversial. We focus on recent findings in genetics, highlight multiple viewpoints regarding the role of… 
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A 42-year-old HIV-positive man who presented with hypo- and hyperpigmented papules and plaques on the upper trunk, head, and neck, with histopathologic findings of epidermodysplasia verruciformis is described.
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Surgical Treatment of Epidermodysplasia Verruciformis
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  • 2010
TLDR
Curettage and application of 35% TCA that was used in these patients has been shown to be an effective and low‐cost alternative, compared to oral, topical, or other physical ablative therapies, with satisfactory cosmetic results and no recurrence during follow‐up.
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A review of the literature will focus on the histologic aspects of viral-associated skin malignancies, as well as the epidemiology, etiology, and clinical aspects of these diseases.
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The unusual case of a Chinese EV patient with concomitant giant genital and axillary warts is described, which is the first reported case of its kind in Asia.
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