Epidermal-like architecture obtained from equine keratinocytes in three-dimensional cultures.

  title={Epidermal-like architecture obtained from equine keratinocytes in three-dimensional cultures.},
  author={Ruchi Sharma and S Z Barakzai and Sarah E Taylor and Francesc Xavier Donadeu},
  journal={Journal of tissue engineering and regenerative medicine},
  volume={10 8},
Despite the high prevalence of skin conditions in the horse, there is a dearth of literature on the culture and biology of equine skin cells, and this is partially attributable to the lack of suitable in vitro skin models. The objective of this study was to develop a three-dimensional (3D) culture system that would support the proliferation and differentiation of equine keratinocytes, similar to that observed in natural epidermis. Cell monolayers were obtained from explants of equine skin and… CONTINUE READING
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