Epidermal label-retaining cells: background and recent applications.

@article{Braun2004EpidermalLC,
  title={Epidermal label-retaining cells: background and recent applications.},
  author={Kristin M. Braun and Fiona M Watt},
  journal={The journal of investigative dermatology. Symposium proceedings},
  year={2004},
  volume={9 3},
  pages={
          196-201
        }
}
Epidermal label-retaining cells (LRC) can be identified by giving neonatal mice repeated injections of 3H-thymidine or 5-bromo-2'-deoxyuridine and then finding the cells that are still labelled in adulthood. Although label retention is simply a marker of the proliferative history of a cell, there is, nevertheless, evidence that it is a characteristic of epidermal stem cells. Here we review the early literature on LRC and then highlight two recent applications. We describe how LRC can be… CONTINUE READING
BETA

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 41 CITATIONS

Similar Papers

Loading similar papers…