Epidermal growth factor stimulates transcription of the c-jun proto-oncogene in rat fibroblasts

@article{Quantin1988EpidermalGF,
  title={Epidermal growth factor stimulates transcription of the c-jun proto-oncogene in rat fibroblasts},
  author={B{\'e}atrice Quantin and R. Breathnach},
  journal={Nature},
  year={1988},
  volume={334},
  pages={538-539}
}
Some growth factor-induced genes, such as the c-fos gene, are activated rapidly and transiently without intervening protein synthesis1. Others, like the rat transin gene2, are activated more slowly but more durably and their activation requires prior protein synthesis. It is tempting to speculate that certain rapidly-activated genes code for transcription factors which interact directly with promoter regions of genes like the transin gene to trigger their expression. Unfortunately, little is… CONTINUE READING

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