Epidermal growth factor receptor mRNA expression in peripheral blood of bladder cancer patients: a potential marker to detect treatment failure.

Recent clinical trials have demonstrated how, despite radical surgery and adjuvant chemotherapy, more than half of muscle invasive bladder cancers develops hematogenous spread and distant metastases. Furthermore, a high percentage of patients with superficial disease has progression to higher stage tumors, which is difficult to predict on the basis of… CONTINUE READING