Epidermal growth factor receptor expression in primary laryngeal cancer: an independent prognostic factor of neck node relapse.

@article{Almadori1999EpidermalGF,
  title={Epidermal growth factor receptor expression in primary laryngeal cancer: an independent prognostic factor of neck node relapse.},
  author={Giovanni Almadori and Gabriella Cadoni and Jacopo Galli and Gabriella Ferrandina and Giovanni Scambia and Georgios Exarchakos and G. Paludetti and Francesco Ottaviani},
  journal={International journal of cancer},
  year={1999},
  volume={84 2},
  pages={188-91}
}
Specimens of laryngeal squamous cell carcinoma (LSCC) were examined for epidermal growth factor receptor (EGFR) content using a radioreceptor method; 140 untreated consecutive patients with primary LSCC undergoing initial surgical resection were followed up for a median of 49 months (range 2-84 months) after surgery. Cox univariate regression analysis using EGFR as a continuous variable showed that EGFR levels were directly associated with the risk of lymph node metastasis. A significant… CONTINUE READING