Epidermal growth factor modulates thyroid growth and function in culture.

Abstract

The effect of epidermal growth factor (EGF) on the growth and function of porcine thyroid follicle suspension cultures was examined. When incubated with EGF (0.01-10 ng/ml), the incorporation of [3H]thymidine was markedly stimulated, with the half-maximal effect occurring at about 0.5 ng/ml. Through 6-day experiments, [3H]thymidine incorporation increased… (More)

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