Epidermal growth factor modulates the lipolytic action of catecholamines in rat adipocytes. Involvement of a Gi protein.

@article{Tebar1993EpidermalGF,
  title={Epidermal growth factor modulates the lipolytic action of catecholamines in rat adipocytes. Involvement of a Gi protein.},
  author={Francesc Tebar and Ignasi Ram{\'i}rez and Maria Soley},
  journal={The Journal of biological chemistry},
  year={1993},
  volume={268 23},
  pages={17199-204}
}
In isolated adipocytes, epidermal growth factor (EGF) did not affect basal (nonstimulated) lipolysis, but interfered with the lipolytic action of isoproterenol (ISO) or glucagon. Similarly, EGF did not affect basal levels of cyclic AMP but interfered with the signal generated by ISO. However, EGF did not affect lipolysis stimulated by forskolin or cyclic… CONTINUE READING