Epidermal growth factor is a potential biomarker for poor cetuximab response in tongue cancer cells.


BACKGROUND Head and neck squamous cell carcinoma is frequently associated with aberrant epidermal growth factor receptor (EGFR) signaling, which contributes to tumor growth. Here, the functional importance of EGFR ligands in relation to proliferation and sensitivity to the EGFR-targeted therapy cetuximab was investigated in three tongue cancer cell lines… (More)
DOI: 10.1111/jop.12310