Epidermal growth factor (EGF) replaces estradiol for the initiation of embryo implantation in the hypophysectomized rat.

@article{Johnson1993EpidermalGF,
  title={Epidermal growth factor (EGF) replaces estradiol for the initiation of embryo implantation in the hypophysectomized rat.},
  author={Donald Clay Johnson and Sankar Nath Chatterjee},
  journal={Placenta},
  year={1993},
  volume={14 4},
  pages={
          429-38
        }
}
Several studies have provided evidence that epidermal growth factor (EGF) or transforming growth factor alpha (TGF alpha) mediate some of the physiological effects of estrogen. The object of the present study was to determine whether exogenous EGF could initiate embryo implantation in the rat, a response known to depend upon the action of estrogen in a progesterone-primed uterus. Immunocytochemical examination showed the presence of immunoreactive EGF, TGF alpha and the EGF receptor in luminal… CONTINUE READING
BETA

Similar Papers

Loading similar papers…