Epidermal and hair follicle progenitor cells express melanoma-associated chondroitin sulfate proteoglycan core protein.

@article{Ghali2004EpidermalAH,
  title={Epidermal and hair follicle progenitor cells express melanoma-associated chondroitin sulfate proteoglycan core protein.},
  author={Lucy Ghali and Soon-Tee Wong and N Tidman and Anthony G. Quinn and Michael P Philpott and Irene M. Leigh},
  journal={The Journal of investigative dermatology},
  year={2004},
  volume={122 2},
  pages={
          433-42
        }
}
Basal keratinocytes in the epidermis and hair follicle are biologically heterogeneous but must include a stable subpopulation of epidermal stem cells. In animal models these can be identified by their retention of radioactive label due to their slow cycle (label-retaining cells) but human studies largely depend on in vitro characterization of colony forming efficiency and clonogenicity. Differential integrin expression has been used to detect cells of increased proliferative potential but… CONTINUE READING

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Emerging Biomarkers in Cutaneous Melanoma

  • Molecular Diagnosis & Therapy
  • 2018
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