Epidermal Neural Crest Stem Cells (EPI-NCSC) and Pluripotency

@article{SieberBlum2008EpidermalNC,
  title={Epidermal Neural Crest Stem Cells (EPI-NCSC) and Pluripotency},
  author={M. Sieber-Blum and Y. Hu},
  journal={Stem Cell Reviews},
  year={2008},
  volume={4},
  pages={256-260}
}
This article serves three purposes. We summarize current knowledge of the origin and characteristics of EPI-NCSC, review their application in a mouse model of spinal cord injury, and we present new data that highlight aspects of pluripotency of EPI-NCSC. EPI-NCSC are multipotent stem cells, which are derived from the embryonic neural crest and are located in the bulge of hair follicles. EPI-NCSC can undergo self-renewal and they are able to generate all major neural crest derivatives, including… Expand
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