Epidermal Growth Factor Receptor in Prostate Cancer Derived Exosomes

@inproceedings{Kharmate2016EpidermalGF,
  title={Epidermal Growth Factor Receptor in Prostate Cancer Derived Exosomes},
  author={Geetanjali D Kharmate and Elham Hosseini-Beheshti and Josselin Caradec and Mei Yieng Chin and Emma S. Tomlinson Guns},
  booktitle={PloS one},
  year={2016}
}
Exosomes proteins and microRNAs have gained much attention as diagnostic tools and biomarker potential in various malignancies including prostate cancer (PCa). However, the role of exosomes and membrane-associated receptors, particularly epidermal growth factor receptor (EGFR) as mediators of cell proliferation and invasion in PCa progression remains unexplored. EGFR is frequently overexpressed and has been associated with aggressive forms of PCa. While PCa cells and tissues express EGFR, it is… CONTINUE READING

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