Epidermal Growth Factor (EGF) intralesional infiltrations: From the bench to the diabetic ulcers cells

@article{BerlangaAcosta2019EpidermalGF,
  title={Epidermal Growth Factor (EGF) intralesional infiltrations: From the bench to the diabetic ulcers cells},
  author={J. Berlanga-Acosta and Y. Mendoza-Mar{\'i} and Ariana Garc{\'i}a-Ojalvo and Jose Angel Acosta-Buxado and Maday Fern{\'a}ndez-Mayola and G. Nieto},
  journal={Integrative molecular medicine},
  year={2019},
  volume={6}
}
Diabetes mellitus remains with an ever-increasing prevalence, indefectibly associated to progressive and irreversible complications. Diabetic lower extremities ulcerations contribute to amputations, disability, and mortality. Ulcers result from a wound healing failure characterized by proliferative arrest, apoptosis, and senescence of granulation tissue-producing cells. Diabetic wounds are also distinguished by an inflamed, toxic, and degradative environment, acting as deterrents for local… Expand
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