Epidemiology of selenium and type 2 diabetes: can we make sense of it?

@article{Rayman2013EpidemiologyOS,
  title={Epidemiology of selenium and type 2 diabetes: can we make sense of it?},
  author={Margaret P. Rayman and Saverio Stranges},
  journal={Free radical biology & medicine},
  year={2013},
  volume={65},
  pages={
          1557-1564
        }
}
The potential of some selenoproteins to protect against oxidative stress led to the expectation that selenium would be protective against type 2 diabetes, and indeed in early in vivo and in vitro studies, selenium (as selenate) was shown to have antidiabetic and insulin-mimetic effects. However, more recently, findings from observational cross-sectional studies have raised concern that high selenium exposure may be associated with type 2 diabetes or insulin resistance, at least in well… CONTINUE READING

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Selenoprotein P expression is controlled through interaction iPlease cite this article

  • B. Speckmann, P. L. Walter, +4 authors H. Steinbrenner
  • Epidemiology of s Biol. Med
  • 2013
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