Epidemiology of cholelithiasis in southern Italy. Part II: Risk factors

  title={Epidemiology of cholelithiasis in southern Italy. Part II: Risk factors},
  author={Giovanni Misciagna and Claudio Leoci and Vito Guerra and Marisa Chiloiro and Silvana Elba and Josephine M. Petruzzi and A Mossa and Maria Rosaria Noviello and Angelo Coviello and Marino Capece Minutolo and V. Mangini and Caterina Messa and Aldo Cavallini and Giampiero De Michele and Italo Giorgio},
  journal={European Journal of Gastroenterology \& Hepatology},
Objective: To determine behavioural, dietary and other common factors associated with new cases of gallstones, diagnosed by ultrasonography, in a prospective cohort study conducted in southern Italy. Subjects and methods: Between May 1985 and June 1986, systematic sampling from the electoral register of Castellana, a small town in southern Italy, yielded 2472 subjects who had had their gallbladder checked for gallstones by ultrasonography. Between May 1992 and June 1993, 1962 out of the 2235… 

Incidence of gallstone disease in Italy: results from a multicenter, population-based Italian study (the MICOL project).

Increasing age and BMI represent true risk factors for gallstone disease (GD); pain in the right hypocondrium and/or epigastrium is confirmed as the only symptom related to gallstones.

Independent Risk Factors for Gallstone Formation in a Region with High Cholelithiasis Prevalence

Female sex, age and being overweight are major risk factors for gallstone formation in this region where cholelithiasis is a frequent disorder, and sex-specific interactions between risk factors were found.

Insulin and gall stones: a population case control study in southern Italy

The results of the study indicate that hyperinsulinaemia may play an important role in the aetiology of gall stones even in individuals without diabetes and with normal serum glucose levels.

Prevalence of cholelithiasis in Buenos Aires, Argentina.

A significant association was found between female gender, age, body mass index, history of colic pain, family history of cholelithiasis, smoking, fatty liver and number of pregnancies in Buenos Aires, capital city of Argentina, is 21.9%.

Epidemiology of Gallstone Disease among Pregnant women in Egypt: Multicenter Study.

Multiple risk factors were found among pregnant women with gallbladder disease and most of them are modifiable.

Are incident gallstones associated to sex‐dependent changes with age? A cohort study

Changes with age in alcohol consumption in females and in reproductive hormones determined incident gallstones, and male reproductive hormones seem to have an impact on incidentgallstones.

Risk factors associated with symptomatic cholelithiasis in Taiwan: a population-based study

The risk factors for cholelithiasis were obesity, hyperlipidemia, hepatitis B infection, hepatitis C infection, and cirrhosis in both genders, and menopause in females, and no unique risk factors were identified among the population of Taiwan.

Clinical correlation of gallstone disease in a Chinese population in Taiwan: experience at Cheng Hsin General Hospital.

Older age, obesity, and type 2 diabetes (FPG > or = 126 mg/dL) are associated with the prevalence of GSD in Taiwan and the prevalence revealed a statistically significant increase with increasing age.

Prospective study of alcohol consumption patterns in relation to symptomatic gallstone disease in men.

It is suggested that frequent, moderate intake of alcohol decreases the risk for symptomatic gallstone disease, in contrast to infrequent or episodic alcohol intake.

Fruit and vegetable consumption and risk of cholecystectomy: a prospective cohort study of women and men

This study supports an inverse association between FV consumption and risk cholecystectomy in women, although the association was restricted to women aged 48–60 years, and in contrast, the study does not support an association in men.