Epidemiology of Human Metapneumovirus in a Pediatric Long-Term Care Facility

  title={Epidemiology of Human Metapneumovirus in a Pediatric Long-Term Care Facility},
  author={Natalie M. Neu and Theresa Plaskett and Gordon Hutcheon and Meghan T. Murray and Karen L. Southwick and Lisa Saiman},
  journal={Infection Control \&\#x0026; Hospital Epidemiology},
  pages={545 - 550}
Background. Viral respiratory pathogens cause outbreaks in pediatric long-term care facilities (LTCFs), but few studies have used viral diagnostic testing to identify the causative pathogens. We describe the use of such testing during a prolonged period of respiratory illness and elucidate the epidemiology of human metapneumovirus (hMPV) at our LTCF. Design. Retrospective study of influenza-like illness (ILI). Setting. A 136-bed pediatric LTCF from January 1 through April 30, 2010. Methods. The… 
Paramyxovirus Outbreak in a Long-Term Care Facility: The Challenges of Implementing Infection Control Practices in a Congregate Setting
OBJECTIVE We report an outbreak of respiratory syncytial virus (RSV) and human metapneumovirus (HMPV) infections in a dementia care ward containing 2 separately locked units (A and B) to heighten
Human metapneumovirus in the preterm neonate: current perspectives
HMPV is a common and important virus in premature infants, and caregivers for preterm infants should consider this virus in patients with acute respiratory symptoms, and HMPV causes nosocomial outbreaks of ARI in hospitals and long-term care facilities.
Nosocomial respiratory viral infections: state of the problems
The biological diversity of the pathogens causing NRVI calls for active promotion of molecular genetics techniques in the work of the laboratory services of health facilities to perform quality etiological diagnosis, design relevant antiviral therapy regimens and effective prevention programs whose implementation will lead to significant reduction in the spread risk of these infections and the treatment costs.
Incidence, Risks, and Types of Infections in Pediatric Long-term Care Facilities
In this study, RTIs were the most common infections diagnosed, but modifiable risk factors forRTIs were not identified and future work should focus on optimizing infection prevention and control strategies to reduce infections, particularly RTIs, in the pediatric long-term care population.
Early Use of Anti-influenza Medications in Hospitalized Children With Tracheostomy
Early use of anti-influenza medications in children with tracheostomy hospitalized with influenza is associated with shorter LOS, but these children continue to receive antibiotics despite identification and treatment of their viral infections.
Developing Case Definitions for Health Care–Associated Infections for Pediatric Long-Term Care Facilities
A pilot study was performed to assess the utility of the SHEA/CDC surveillance case definitions for children in pLTCFs, which noted that definitions should be created for the pL TCF population.
Health care–associated infection outbreaks in pediatric long-term care facilities
Infection prevention issues in long-term care
  • L. Nicolle
  • Medicine
    Current opinion in infectious diseases
  • 2014
The extent to which endemic infections or antimicrobial resistance in long-term care facilities can be prevented remains unclear and efforts to limit infections in these facilities should focus on outbreak prevention and standard procedures for environmental cleaning, food preparation, and hand hygiene.
Impact of Infection Prevention and Control Initiatives on Acute Respiratory Infections in a Pediatric Long-Term Care Facility
ARIs did not decrease overall, though the proportion of infections associated with outbreaks and average number of cases per outbreak decreased, and Influenza rates decreased significantly.


An outbreak of severe respiratory tract infection due to human metapneumovirus in a long-term care facility.
  • G. Boivin, G. De Serres, C. Couture
  • Medicine, Biology
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
  • 2007
HMPV can be associated with important outbreaks of acute respiratory tract infection in elderly institutionalized persons and has the potential to cause fatal cases in patients with possible cases.
Comparison of Human Metapneumovirus, Respiratory Syncytial Virus and Influenza A Virus Lower Respiratory Tract Infections in Hospitalized Young Children
The clinical pattern of HMPV more closely resembles that of RSV than that of influenza A LRI, yet the differences in age, radiographic findings and clinical diagnosis suggest that H MPV pathogenesis may differ from that ofRSV.
Outbreak of Human Metapneumovirus Infection in Norwegian Children
Upper respiratory tract infections and mild to severe bronchiolitis were most common, but a relatively high proportion of hospitalized children developed severe pneumonia, and hMPV was the most common virus isolate during the winter season 2002 to 2003 in children hospitalized for respiratory tract infection.
Human Metapneumovirus Infection in Young Children Hospitalized With Acute Respiratory Tract Disease: Virologic and Clinical Features
Evidence is provided of the importance of hMPV as a pathogen associated with ARI in young children during 2 consecutive winter-spring seasons and in cases of pneumonia is suspected.
A summer outbreak of human metapneumovirus infection in a long-term-care facility.
Human metapneumovirus (hMPV), a recently discovered paramyxovirus, is thought to be primarily a winter-spring pathogen affecting young children with a clinical presentation similar to that of
It is shown that among children <5 years of age attending a day care center during a 1-year period, seven children were infected by hMPV and this virus accounted for 2.1% of the ARI episodes.
Recurrent outbreak of pandemic (H1N1) 2009 virus infection in a pediatric long-term care facility and the adjacent school.
A doubleblind, randomized comparison of levofloxacin 750 mg once daily for five days with ciprofloxacins 400/500 mg twice-daily for 10 days for the treatment of complicated urinary tract infections and acute pyelonephritis.
Human metapneumovirus and lower respiratory tract disease in otherwise healthy infants and children.
Human metapneumovirus infection is a leading cause of respiratory tract infection in the first years of life, with a spectrum of disease similar to that of respiratory syncytial virus.
Novel influenza A(H1N1) in a pediatric health care facility in New York City during the first wave of the 2009 pandemic.
The burden of care experienced by the pediatric health care facility in New York, New York from May 3, 2009 to July 31, 2009, during the novel influenza A(H1N1) pandemic can be compared with the disease severity of subsequent waves of the 2009 novel flu pandemic.
An Outbreak of Adenovirus Type 7 in a Residential Facility for Severely Disabled Children
The epidemiologic investigation revealed that all the 8 affected children shared a playroom and a caregiver worked with them while suffering fever, sore throat, and conjunctivitis before the onset of the outbreak, indicating that Adenovirus type 7 may cause short outbreaks of infection in institutions, causing children to develop life-threatening disease.