Epidemiology and quantitative risk assessment: a bridge from science to policy.

@article{HertzPicciotto1995EpidemiologyAQ,
  title={Epidemiology and quantitative risk assessment: a bridge from science to policy.},
  author={Irva Hertz-Picciotto},
  journal={American journal of public health},
  year={1995},
  volume={85 4},
  pages={484-91}
}
Quantitative risk assessment provides formalized scientific input to regulatory agencies that set occupational and environmental standards for potentially toxic exposures. Current practice relies heavily on statistical extrapolation from high-dose animal studies. Human data obviate the need for interspecies extrapolation and reduce the range of high-to-low dose extrapolation. This paper proposes a framework for classifying individual epidemiologic studies as to their adequacy for use in dose… CONTINUE READING

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