Epidemiology and pathophysiology of mitral valve prolapse: new insights into disease progression, genetics, and molecular basis.

@article{Delling2014EpidemiologyAP,
  title={Epidemiology and pathophysiology of mitral valve prolapse: new insights into disease progression, genetics, and molecular basis.},
  author={Francesca N. Delling and Ramachandran S. Vasan},
  journal={Circulation},
  year={2014},
  volume={129 21},
  pages={2158-70}
}
M itral valve (MV) prolapse (MVP) is a common disorder, afflicting 2% to 3% of the general population. It is characterized by typical fibromyxomatous changes in the mitral leaflet tissue with superior displacement of 1 or both leaflets into the left atrium. 3,4 With a prevalence of 2% to 3%, MVP is expected to affect ≈7.8 million individuals in the United States and >176 million people worldwide. MVP can be associated with significant mitral regurgitation (MR), bacterial endocardi-tis… CONTINUE READING