Epidemiology and pathogenesis of influenza.
@article{Zambon1999EpidemiologyAP, title={Epidemiology and pathogenesis of influenza.}, author={M. Zambon}, journal={The Journal of antimicrobial chemotherapy}, year={1999}, volume={44 Suppl B}, pages={ 3-9 } }
Influenza A, B and C all have a segmented genome, although only certain influenza A subtypes and influenza B cause severe disease in humans. The two major proteins of influenza are the surface glycoproteins-haemagglutinin (HA) and neuraminidase (NA). HA is the major antigen for neutralizing antibodies and is involved in the binding of virus particles to receptors on host cells. Pandemics are a result of novel virus subtypes of influenza A, created by reassortment of the segmented genome… Expand
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