Epidemiology and outcome of cervical dystonia (spasmodic torticollis) in Rochester, Minnesota

  title={Epidemiology and outcome of cervical dystonia (spasmodic torticollis) in Rochester, Minnesota},
  author={David W. Claypool and Drake D. Duane and Duane M. Ilstrup and L. Joseph Iii Melton},
  journal={Movement Disorders},
The natural history of cervical dystonia (spasmodic torticollis) was investigated in a population‐based study in Rochester, Minnesota. Eleven new cases were identified with onset during the 20‐year period 1960–1979. The overall incidence rate was 1.2 per 100,000 person‐years (95% confidence interval 0.5–1.9) with a female: male ratio of age‐adjusted incidence rates of 3.6:1. A unitary etiology was not apparent: injury antedated onset in four of the 11 patients, whereas six had documented… 
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Disease Progression of Idiopathic Cervical Dystonia in Spite of Improvement After Botulinum Toxin Therapy
Patients experience a progression of CD, but recognize improvement of abnormal head position due to BoNT-therapy, the poorer is the long-term outcome independent on duration of BoNT treatment.
Causes for Treatment Delays in Dystonia and Hemifacial Spasm: A Canadian Survey
  • M. Jog, S. Chouinard, S. Simonyi
  • Medicine, Psychology
    Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques
  • 2011
Survey results show that diagnosis of dystonias or of HFS, and therefore, access to treatment, is delayed, and an educational program for primary care physicians may be helpful to decrease the time to diagnosis and referral to a specialist centre for treatment.
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Idiopathic cervical dystonia: Clinical characteristics
Because the cervical dystonia in 38% of patients is not spasmodic, it is proposed that the term “spas modic torticollis” is not a completely appropriate designation for this condition.
Spontaneous remissions in spasmodic torticollis
Spontaneous remissions in the course of spasmodic torticollis seem to be more frequent in patients with early onset, and they occur usually during the first year, while in the non-remission group, 18 patients were Jewish.
The clinical course of spasmodic torticollis
The study population was exposed to a wide variety of therapeutic interventions that had little, if any, obvious clinical effect, and the remaining 13 patients had no significant improvement in their disease.
Cervical dystonia
Anticholinergic drugs provided moderate improvement in 33% of patients, but local intramuscular botulinum toxin injections relieved CD, local pain, or both in over 90% of all treated patients.
A genetic study of idiopathic focal dystonias
A genetic study of idiopathic focal dystonia was undertaken by examining 153 first‐degree relatives of 40 index patients with torticollis, other focal cranial dystonias, and writer's cramp, suggesting the presence of an autosomal dominant gene or genes with reduced penetrance as a common cause.
Spasmodic Torticollis — Review of 220 Patients
In most areas, including female preponderance and frequency of postural tremor, the findings confirmed previous studies and highlighted particular points: importance of psychopathological antecedents and association with stressful life-events.
Dystonia and tremor induced by peripheral trauma: predisposing factors.
In 15 patients with dystonia or tremor in whom the onset of abnormal movements was related, in time and in distribution, to injury of a body part, possible predisposing factors may have contributed to the pathogenesis of the trauma induced abnormal involuntary movements.
Pathology in brainstem regions of individuals with primary dystonia
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Delayed-onset dystonia in patients with "static" encephalopathy.
Eight cases of persistent dystonia appearing one to 14 years after non-progressive cerebral insults are described. Five were due to perinatal anoxia, one to trauma, and two to cerebral infarction.
Epidemiology of focal and generalized dystonia in Rochester, Minnesota
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