Epidemiology and natural history of human papillomavirus infections and type-specific implications in cervical neoplasia.

@article{Bosch2008EpidemiologyAN,
  title={Epidemiology and natural history of human papillomavirus infections and type-specific implications in cervical neoplasia.},
  author={Francesc Xavier Bosch and Ann N. Burchell and Mark Schiffman and Anna Regina Giuliano and Silvia de Sanjos{\'e} and Laia Bruni and Guillermo Tortolero-Luna and Susanne Kr{\"u}ger Kjaer and Nubia Mu{\~n}oz},
  journal={Vaccine},
  year={2008},
  volume={26 Suppl 10},
  pages={K1-16}
}
Worldwide human papillomavirus (HPV) prevalence in women with normal cytology at any given point in time is approximately 10% indicating that HPV is one of the most common sexually transmitted infections. HPV-16 is consistently the most common type and HPV-18 the second with some minor regional differences. Furthermore, across the spectrum of cervical lesions, HPV-16 is consistently the most common HPV type contributing to 50-55% of invasive cervical cancer cases strongly suggesting that this… CONTINUE READING
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