Epidemiology and molecular pathology of glioma

  title={Epidemiology and molecular pathology of glioma},
  author={Judith Schwartzbaum and James L. Fisher and Kenneth D. Aldape and Margaret R. Wrensch},
  journal={Nature Clinical Practice Neurology},
Gliomas account for almost 80% of primary malignant brain tumors, and they result in more years of life lost than do any other tumors. Glioblastoma, the most common type of glioma, is associated with very poor survival, so glioma epidemiology has focused on identifying factors that can be modified to prevent this disease. Only two relatively rare factors have so far been conclusively shown to affect glioma risk—exposure to high doses of ionizing radiation, and inherited mutations of highly… CONTINUE READING
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