Epidemiology and individual susceptibility to adverse drug reactions affecting the liver.

@article{Larrey2002EpidemiologyAI,
  title={Epidemiology and individual susceptibility to adverse drug reactions affecting the liver.},
  author={Dominique G Larrey},
  journal={Seminars in liver disease},
  year={2002},
  volume={22 2},
  pages={
          145-55
        }
}
Adverse drug reactions affecting the liver represent an important challenge for safety in drug development. Drugs can reproduce practically the whole spectrum of liver diseases, but acute hepatitis is the most common syndrome. Drug hepatotoxicity is one of the most common causes of fulminant hepatitis. Most hepatic drug reactions occur in only a small proportion of individuals, making them difficult to detect at the time of drug development. Liver injury is principally recognized on the basis… CONTINUE READING
BETA

Similar Papers

Citations

Publications citing this paper.
SHOWING 1-10 OF 116 CITATIONS, ESTIMATED 38% COVERAGE

Case-crossover design: an alternative strategy for detecting drug-induced liver injury.

  • Journal of clinical epidemiology
  • 2012
VIEW 5 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

[An analysis of the causes, characteristics, and consequences of reexposure to a drug or compound responsible for a hepatotoxicity event].

  • Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva
  • 2008
VIEW 6 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Lifrarskaði af völdum lyfja

VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Review article: drug-induced liver injury in clinical practice.

  • Alimentary pharmacology & therapeutics
  • 2010
VIEW 3 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

An official ATS statement: hepatotoxicity of antituberculosis therapy.

  • American journal of respiratory and critical care medicine
  • 2006
VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

FILTER CITATIONS BY YEAR

2002
2019

CITATION STATISTICS

  • 10 Highly Influenced Citations

  • Averaged 7 Citations per year over the last 3 years

  • 20% Increase in citations per year in 2019 over 2018