Epidemiology and differential diagnosis of NSAID-induced injury to the mucosa of the small intestine.

@article{Smale2001EpidemiologyAD,
  title={Epidemiology and differential diagnosis of NSAID-induced injury to the mucosa of the small intestine.},
  author={Simon Smale and Jeremy A Tibble and Gudmundur Sigthorsson and Ingvar Iain Bjarnason},
  journal={Best practice & research. Clinical gastroenterology},
  year={2001},
  volume={15 5},
  pages={723-38}
}
Non-steroidal anti-inflammatory drugs cause small-bowel inflammation in about 60% of patients receiving these drugs long-term. The inflammation is associated with small intestinal bleeding, protein loss, ulcers and occasionally strictures. Treatment options for NSAID enteropathy include metronidazole, sulphasalazine and misoprostol, and some patients may require surgery. The diagnosis of NSAID enteropathy is not always straightforward. It is especially difficult to differentiate it from the… CONTINUE READING