Epidemiology, biologic behavior, and natural history of mesothelioma.


Malignant pleural mesothelioma has a well described natural history but poorly defined pathogenesis. It is strongly associated with asbestos exposure. A predominantly locally invasive disease, the success of more aggressive life-prolonging therapies has increased the potential for the development of distant metastases in survivors. Recently described new… (More)


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@article{Zellos2004EpidemiologyBB, title={Epidemiology, biologic behavior, and natural history of mesothelioma.}, author={Lambros S Zellos and David C. Christiani}, journal={Thoracic surgery clinics}, year={2004}, volume={14 4}, pages={469-77, viii} }