Epidemiological studies of Streptococcus pneumoniae in infants: development of antibody to phosphocholine.

@article{Gray1983EpidemiologicalSO,
  title={Epidemiological studies of Streptococcus pneumoniae in infants: development of antibody to phosphocholine.},
  author={Barry Gray and Hugh C. Dillon and David E. Briles},
  journal={Journal of clinical microbiology},
  year={1983},
  volume={18 5},
  pages={1102-7}
}
The pneumococci possess, in addition to type-specific capsular polysaccharides, a number of antigens common to the species. Antibodies to phosphocholine (PC), a major determinant of the C-carbohydrate, have been shown to protect mice from experimental pneumococcal infection, but little is known of the role of anti-PC antibodies in humans or the extent to… CONTINUE READING