Epidemiological pathology of Tau in the ageing brain: application of staging for neuropil threads (BrainNet Europe protocol) to the MRC cognitive function and ageing brain study

Abstract

INTRODUCTION Deposition of abnormally phosphorylated tau (phospho-tau) occurs in Alzheimer's disease but also with brain ageing. The Braak staging scheme focused on neurofibrillary tangles, but abundant p-tau is also present in neuropil threads, and a recent scheme has been proposed by the BrainNet Europe consortium for staging tau pathology based on… (More)
DOI: 10.1186/s40478-016-0275-x

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@inproceedings{Wharton2016EpidemiologicalPO, title={Epidemiological pathology of Tau in the ageing brain: application of staging for neuropil threads (BrainNet Europe protocol) to the MRC cognitive function and ageing brain study}, author={Stephen Barrie Wharton and Tha{\'i}s Soares Cianciarullo Minett and David A Drew and Gillian Forster and Fiona E. Matthews and Carol Brayne and Paul G. Ince}, booktitle={Acta neuropathologica communications}, year={2016} }