Epidemiological evidence that physical activity is not a risk factor for ALS

@article{Hamidou2014EpidemiologicalET,
  title={Epidemiological evidence that physical activity is not a risk factor for ALS},
  author={Bello Hamidou and Philippe Couratier and Cyril Besançon and Marie Nicol and Pierre-Marie Preux and Ben{\^o}it Marin},
  journal={European Journal of Epidemiology},
  year={2014},
  volume={29},
  pages={459-475}
}
To elucidate whether physical activity (PA) and sport increase the risk of developing amyotrophic lateral sclerosis (ALS), a literature review of epidemiological studies was conducted according to the Meta-analysis of Observational Studies in Epidemiology guidelines. Six databases (Pubmed, Scopus, ScienceDirect, IngentaConnect, Refdoc and the Cochrane database) were searched to April 2014. Experts were asked to identify studies in press. Studies of interest were examined for their level of… Expand
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The Amyotrophic Lateral Sclerosis (ALS) is a chronic and progressive neuro-degenerative pathology that starts in adult age and usually leads patients to death for respiratory distress after 3 yearsExpand
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An increased risk of ALS with higher levels of leisure time physical activity was found and the lack of association with occupational physical activity and the absence of a dose–response relationship strengthen the hypothesis that not increased physical activity per se but rather a genetic profile or lifestyle promoting physical fitness increases ALS susceptibility. Expand
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